I've never heard of anyone get a mercedes V8 to run well on carbies, and a few have tried.Not too worried about the value of the car (my fantastic condition 280S would be lucky to get $8-9k - anything else V8 in comparable condtion would be $25k+), I'm not too keen on playing with EFI, may be the only option though.
Not saying its impossible, but have never seen it. Since they never made a carby version, there are no factory parts.
If you want to V8 swap your car, I would personally buy a K-jet motor. K-jet is quite simple and requires a lot less electrics than D-jet, and most troubleshooting can be done with basic fuel pressure gauges. Go with regular K, not KE. A 380 may be a go, as being an alloy motor will probably weigh similar to the M110 and it has a four speed transmission. The iron block 350/450 are quite heavy. Rusty 380SE/SELs are often being wrecked and parts cars are quite cheap.
even better get a whole 380SE/SEL parts car.